Persistent organic
pollutants (POPs) are chemical substances that persist in the environment, bio-accumulate
through the food chain, and are deleterious to the environment and to human
health (1). The Stockholm Convention, an
international treaty signed in 2001, established a list of the 12 most serious POPs
in order to enforce proper management/disposal, at the very least (1). This “dirty dozen” includes dioxins, a family
of industrial byproduct chemicals, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin
(TCDD) (2). TCDD, previously linked to
reproductive health issues (among other things), is found more abundantly as it
moves up the food chain (2).
In August of this year, a
study was published in Occupational &
Environmental Medicine that studies the effect of TCDD exposure on the
ratio of male-to-female offspring of those exposed (3). The study back-calculated serum TCDD
concentration of 244 voluntary participants who worked in an herbicide
production plant between 1969 and 1984 (3).
The data ultimately analyzed included 355 births from 127 biological
fathers and only 21 biological mothers (3).
While the results of the
study found no statistically significant effect of serum TCDD concentration in
women, they do indicate that a serum TCDD level above 20 pg/g in men was
associated with the birth of fewer boys relative to girls (3). However, limited studies on the endocrine/reproductive
effects of TCDD, an overall scarcity of research in this area, and severe methodological
drawbacks (e.g. model estimations of serum TCDD at time of conception), should
be considered.
A month later, the Huffington
Post published an article entitled “Men Exposed to This Herbicide Chemical May
Be Less Likely to Have Sons” (4).
Despite the obvious click-bait nature of the title, the article is
reasonably well-written. The author,
Lisa Rapaport, simplifies the science for a non-scientific audience, and includes
caveats about sample sizes, contradictory studies, and an overall lack of
available research (4). For example, she
concisely defines dose-dependence as, “the higher the dioxin exposure, the
bigger the effect” (4). Fruther, she is
critical of the sample size of women in the study, mentions that few studies of
this nature have been done, and that some of the others do not observe the same
effects.
Rapaport is a member of the
Center for Health Journalism, an organization that extensively trains
journalists how to approach science in the news. She presents the information
effectively while being critical of the underlying science. As a result, despite HuffPo’s sensationalist
nature and several missed opportunities to be even more critical, I give this
article an 8/10 for Rapaport’s reasonably critical and efficient approach to
the study.
Works Cited
1. "Persistent Organic Pollutants (POPs)." UNEP.
United Nations Environment Programme, n.d. Web. 25 Nov. 2016. <http://www.unep.org/chemicalsandwaste/POPsold/tabid/1059787/Default.aspx>.
2. "Dioxins and Their Effects on Human Health." World
Health Organization. World Health Organization, n.d. Web. 25 Nov. 2016.
<http://www.who.int/mediacentre/factsheets/fs225/en/>.
3. Mannetje, Andrea รขT, Amanda Eng, Chris Walls, Evan Dryson,
Manolis Kogevinas, Collin Brooks, Dave Mclean, Soo Cheng, Allan H. Smith, and
Neil Pearce. "Sex Ratio of the Offspring of New Zealand Phenoxy Herbicide
Producers Exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin." Occup
Environ Med Occupational and Environmental Medicine (2016): 1-6. Web.
4. Rapaport, Lisa. "Men Exposed To This Herbicide Chemical
May Be Less Likely To Have Sons." Huffington Post. Huffington
Post, 30 Sept. 2016. Web. 25 Sept. 2016. <http://www.huffingtonpost.com/entry/men-exposed-to-this-herbicide-chemical-may-have-fewer-sons_us_57eea9d7e4b024a52d2ec72a>.